Does Eurycoma Longifolia Actually Boost Testosterone? New Research [2025]

Eurycoma longifolia testosterone research delivers measurable results for men facing hormonal challenges. Hypogonadism affects 1.2% to 12.8% of middle-aged and older men [2]. Only 10% receive proper treatment in the USA and Europe [2].

Meta-analysis data reveal significant testosterone increases in men supplementing with Eurycoma longifolia. Total testosterone levels showed substantial improvement: SMD = 1.352, 95% CI 0.565 to 2.138, p = 0.001 [2]. These results appeared consistently in healthy volunteers and men with diagnosed hypogonadism [2].

Clinical studies document notable improvements in free testosterone levels. One trial recorded increases from 247 ± 126 pg/mL to 305 ± 180 pg/mL after treatment [2]. Researchers examined 150 articles on the subject. Eleven met the quality inclusion criteria. Most were randomized placebo-controlled trials showing considerable effects on male sexual health [28].

Scientific evidence supports what traditional medicine has recognized for centuries. Tongkat Ali (Eurycoma longifolia) offers measurable benefits for testosterone optimization. The research data confirms its effectiveness as a natural alternative to conventional hormone therapy...

Got questions? Ask the author in the comments section at the bottom of this page.

Understanding Testosterone and Hypogonadism

Testosterone functions as the primary male sex hormone. Testicles produce this essential androgen, which stimulates masculine characteristics and maintains critical bodily functions [2]. This hormone plays a crucial role in developing and maintaining sex organs, muscle mass, bone density, red blood cell levels, and reproductive function [2].

What is testosterone and why it matters

Your body maintains testosterone levels through precise hormonal control. The hypothalamus releases gonadotropin-releasing hormone (GnRH). This triggers the activation of the pituitary gland, releasing luteinizing hormone (LH). LH travels to the testicles, stimulating testosterone production [2]. This system ensures proper development during puberty and influences health throughout life.

Normal testosterone ranges between 300 and 1,000 ng/dL. Morning levels peak highest [2]. Beyond reproductive health, testosterone regulates cognitive function, mood, and metabolism. It maintains energy levels, muscle strength, and controls fat distribution [28].

Symptoms and causes of low testosterone

Male hypogonadism occurs when testosterone drops below 300 ng/dL [5]. Symptoms significantly impact quality of life:

• Reduced sex drive and erectile dysfunction
• Decreased muscle mass and increased body fat
• Fatigue and reduced energy levels
• Mood changes, including irritability and depression
• Loss of body hair and potential gynecomastia development
• Decreased bone mineral density [2]

Two categories define the causes. Primary hypogonadism results from testicular dysfunction preventing normal testosterone production [2]. Secondary hypogonadism involves problems with the hypothalamus or pituitary gland [2]. Contributing factors include aging, obesity, type 2 diabetes, sleep apnea, medications, and chronic illnesses [2].

Prevalence of hypogonadism in men

Hypogonadism affects substantial male populations. Approximately 2% of men overall have low testosterone [2]. Prevalence increases dramatically with age - over 8% of men between 50-79 years develop hypogonadism [2].

Specific populations show higher rates. 30% of obese men have low testosterone compared to 6.4% with normal weight [5]. Testosterone deficiency affects 24.5% of diabetic men versus 12.6% without diabetes [2]. Up to 50% of men over 80 years experience testosterone deficiency [28].

Despite this prevalence, treatment remains inadequate. Only 5% of men with low testosterone receive replacement therapy [28]. This highlights the critical need for awareness and proper diagnosis of hormonal deficiencies.

Why Eurycoma Longifolia is Gaining Attention

Traditional herbal medicine has recognized Eurycoma longifolia for centuries across Southeast Asia. Modern science now validates these ancient applications.

Traditional uses of Tongkat Ali

Eurycoma longifolia (Tongkat Ali or Malaysian ginseng) served as a cornerstone remedy throughout Malaysia, Indonesia, and Vietnam [28]. Each plant part offered specific therapeutic benefits:

• Roots treated high blood pressure, fever, and served as post-delivery tonics
• Leaves provided relief from itching through decoctions
• Fruits addressed dysentery conditions
• Bark functioned as a vermifuge treatment

Traditional practitioners primarily valued Tongkat Ali for aphrodisiac effects and male sexual dysfunction treatments [2]. Root extracts have been used to address conditions ranging from malaria to cancer, diabetes, anxiety, exercise recovery, and osteoporosis [28].

Modern interest in herbal testosterone boosters

Natural testosterone boosters dominate today's supplement market. Herbal-based formulations accounted for 45.0% of the market revenue in 2023 [5]. Men seek alternatives to synthetic supplements that cause liver damage and cardiovascular complications.

Tongkat Ali appears in over 700 herbal products marketed as aphrodisiacs [2]. This popularity reflects the fact that 80% of people worldwide rely on herbal medicines for their primary healthcare needs [28].

Convenient formulations now include tea and coffee additives. Malaysia's National Pharmaceutical Control Bureau registers over 200 products containing Eurycoma longifolia [28].

What makes LJ100® different

LJ100® represents precision standardization of traditional Tongkat Ali. This proprietary freeze-dried water extract contains standardized 0.8–1.5% eurycomanone [2].

Eurycomanone derivatives increase testosterone levels while exhibiting anti-estrogenic activity that improves spermatogenesis [2]. Eurycoma longifolia doesn't affect urinary testosterone glucuronide ratios, ensuring compliance with international sports doping policies [2].

Standardization combined with scientific validation creates evidence-based natural testosterone support...

What the Research Says: Clinical Trials and Meta-Analysis

Scientific evidence supporting Eurycoma longifolia's testosterone-boosting effects has expanded significantly. Clinical trials validate traditional practitioners' understanding of the hormonal benefits of this botanical.

Overview of recent testosterone studies

Nine significant studies published between 2012 and 2021 investigated Eurycoma longifolia's effects on testosterone levels [2]. Study designs varied from comparative prospective trials to double-blind controlled experiments. Seven out of nine studies reported significant improvements in total testosterone levels after Eurycoma longifolia supplementation [2].

Research protocols spanned dosages from 100-600mg daily with treatment durations ranging from two weeks to six months. This extensive research foundation establishes the herb's consistent effectiveness across multiple parameters.

Results from randomized controlled trials

Randomized controlled trials demonstrate measurable outcomes. Healthy volunteers with testosterone below 300 ng/dL showed significant improvements after taking 100mg or 200mg daily for 12 weeks compared to placebo [2]. A six-month trial using 200mg daily supplementation significantly increased testosterone levels in men with poor Androgen Deficiency in the Aging Male (ADAM) scores [2].

Health Natura's Testosterone Matrix Daily Support contains a therapeutic dose of LJ100 to support your testosterone levels properly.

Shorter interventions prove equally effective. A 600mg daily treatment for 14 days produced meaningful intragroup increases in testosterone [2]. Protocol consistency across different studies confirms the herb's reliability.

Meta-analysis findings on testosterone increase

Meta-analysis of five RCTs provides the strongest evidence. Random model effect revealed significant increases in total testosterone levels (SMD = 1.352, 95% CI 0.565 to 2.138, p = 0.001) in men receiving Eurycoma longifolia supplementation [2] [6]. This statistical measure indicates a substantial clinical effect size beyond mere statistical significance. Researchers concluded Eurycoma longifolia supplementation represents "a safe and promising therapeutic option" for testosterone production enhancement [6].

Subgroup analysis: healthy vs hypogonadal men

Benefits appear particularly pronounced for specific populations. Subgroup analysis revealed increased testosterone levels in both healthy men and those with hypogonadism (testosterone < 300 ng/dL). Improvements were statistically significant primarily in the hypogonadism group [2]. Eurycoma longifolia proves especially valuable for men with clinically low testosterone levels rather than those seeking enhancement from normal baselines.

How Eurycoma Longifolia May Work

Eurycoma longifolia operates through multiple biochemical pathways to enhance testosterone production. These mechanisms target specific hormonal systems within the male endocrine network.

Stimulation of LH and FSH

The hypothalamic-pituitary-gonadal (HPG) axis controls testosterone production. Eurycoma longifolia activates this pathway when the hypothalamus releases gonadotropin-releasing hormone (GnRH), stimulating pituitary gland release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1]. LH then signals testicular Leydig cells to produce testosterone. Research on rats confirms eurycoma longifolia extract triggers this axis, decreasing plasma estrogen while increasing testosterone, LH, and FSH levels [7].

Young adults taking tongkat ali supplements show different response patterns. Some trials documented increased testosterone without corresponding LH and FSH elevation [8]. These findings suggest eurycoma longifolia works through the hypothalamic-pituitary-adrenal axis in younger populations [8].

Reduction in SHBG levels

Sex hormone-binding globulin (SHBG) binds 40-50% of circulating testosterone, rendering it biologically unavailable [1]. Eurycoma longifolia influences the release rate of "free" testosterone from SHBG [9]. This herb primarily functions as a testosterone "restorer" rather than a "booster" by releasing bound testosterone to maintain normal levels [9].

Inhibition of the aromatase enzyme

Eurycomanone, the active component, inhibits the aromatase enzyme [10]. This enzyme converts testosterone to estrogen, reducing available testosterone. Eurycomanone blocks this conversion, preserving testosterone levels [7]. Scientific studies demonstrate eurycomanone enhances testosterone steroidogenesis in Leydig cells through aromatase-inhibiting action [10].

Impact on free vs total testosterone

Biologically active "free" testosterone represents only 2-3% of total testosterone [1]. After two weeks of tongkat ali supplementation, subjects experienced 15% higher total testosterone and 34% increased free testosterone levels [11]. Eurycoma longifolia particularly enhances the bioavailable testosterone portion that cells can utilize.

Does Tongkat Ali Increase Testosterone?

Clinical studies examining Tongkat Ali's testosterone-boosting effects deliver compelling results across diverse populations. The evidence speaks clearly.

Impact on hypogonadal men

Men with hypogonadism show the most dramatic benefits. Subgroup analysis confirmed significant testosterone increases specifically in the hypogonadism subgroup (testosterone < 300 ng/dL) [2]. One study showed testosterone levels increased in almost 50% of participants with androgen deficiency after taking 200mg daily for 6 months [14].

The 200mg daily dosage consistently yielded superior results for those with clinically low testosterone levels [2]...

Other Benefits Beyond Testosterone

Eurycoma longifolia delivers additional health improvements beyond hormonal optimization.

Improved libido and sexual function

Clinical research documents significant erectile function improvements with Eurycoma longifolia supplementation. Meta-analysis of 139 participants showed meaningful IIEF-5 score increases, particularly among men with lower baseline erectile function [15]. A review of 11 studies confirmed the effectiveness for treating various male sexual disorders [16].

Better mood and reduced stress

Eurycoma longifolia supplementation (200 mg daily) reduces cortisol exposure by 16%. Testosterone status increased by 37% [17]. Mood improvements include tension reduction by 11%, anger by 12%, and confusion by 15% [17]. The herb effectively shields the body from chronic stress, whether from daily pressures, dieting, or exercise training [4].

Enhanced sperm quality and fertility

Male fertility markers show substantial improvements with Eurycoma longifolia. Clinical research demonstrates significant increases in sperm concentration, motility, and percentage of morphologically normal sperm [18]. A study involving 75 couples with infertility found that 200 mg daily supplementation helped achieve spontaneous pregnancy in 14.7% of cases after three months [19].

Potential athletic performance support

Physical performance benefits include increased lean mass and muscular strength [20]. Combined Eurycoma longifolia supplementation with concurrent training improved muscular strength in men with androgen deficiency [21]. Endurance cyclists experienced a 32% cortisol reduction while increasing testosterone by 16%, creating a favorable anabolic environment [4].

These additional benefits make Eurycoma longifolia more than just a testosterone optimizer...

Conclusion

Eurycoma longifolia represents a scientifically validated natural solution for men facing testosterone challenges. Clinical evidence confirms its effectiveness across multiple populations. Men with clinically low testosterone levels experience the most pronounced benefits.

The 200mg daily dosage delivers consistent results for hypogonadal men. This therapeutic amount increases both total and free testosterone levels. Free testosterone improvements matter most—this bioavailable form drives improvements in energy, mood, and sexual function.

Research validates what traditional practitioners have understood for centuries. Eurycoma longifolia works through natural pathways. It stimulates your body's hormone production systems rather than introducing synthetic compounds. This approach avoids the dependency issues and negative feedback loops associated with external hormone replacement.

Standardized extracts like LJ100® ensure reliable potency and consistent results. These refined preparations maintain the precise eurycomanone content necessary for therapeutic effects. Quality standardization makes the difference between traditional preparations and modern supplements.

The benefits extend beyond testosterone optimization. Cortisol reduction, improved sperm quality, enhanced sexual function, and mood support create a complete male vitality profile. This multi-target approach addresses the interconnected nature of hormonal health.

Men seeking natural alternatives to synthetic hormone therapy have a proven option. The growing body of research supports its safety profile and effectiveness. Age-related testosterone decline responds particularly well to this approach...

Key Takeaways

Recent clinical research provides strong evidence that Eurycoma longifolia (Tongkat Ali) can effectively boost testosterone levels, particularly for men with hormonal deficiencies.

• Meta-analysis confirms testosterone boost: Studies show significant increases in total testosterone (SMD = 1.352, p = 0.001) across multiple clinical trials with 232 participants.

• Most effective for hypogonadal men: Men with testosterone below 300 ng/dL experience the greatest benefits, with a 200mg daily dosage showing superior results.

• Increases bioavailable testosterone: Tongkat Ali enhances free testosterone by 34% in just two weeks, making more hormone available for cellular use.

• Works through natural pathways: Unlike synthetic hormones, it stimulates your body's natural testosterone production via the hypothalamic-pituitary-gonadal axis without dependency risks.

• Offers comprehensive male health benefits: Beyond testosterone, it improves sexual function, reduces cortisol by 16%, enhances sperm quality, and supports mood and energy levels.

The research validates traditional use while providing modern men with a scientifically backed natural alternative to synthetic hormone replacement therapy.

FAQs

Q1. How does Eurycoma longifolia affect testosterone levels in men? Eurycoma longifolia has been shown to significantly increase total testosterone levels, particularly in men with hypogonadism (testosterone below 300 ng/dL). Clinical studies have demonstrated improvements in both total and free testosterone, with some research showing up to a 34% increase in free testosterone after just two weeks of supplementation.

Q2. What is the recommended dosage of Eurycoma longifolia for boosting testosterone? Based on clinical research, a daily dosage of 200mg of Eurycoma longifolia extract has consistently shown the best results, especially for men with low testosterone levels. This dosage has been effective in improving testosterone levels over periods ranging from 2 weeks to 6 months in various studies.

Q3. Are there any benefits of Eurycoma longifolia beyond testosterone enhancement? Yes, Eurycoma longifolia offers several additional benefits. It has been shown to improve libido and sexual function, reduce stress by lowering cortisol levels, enhance mood, increase sperm quality and fertility, and potentially support athletic performance by increasing fat-free mass and muscular strength.

Q4. Is Eurycoma longifolia safe for long-term use? Eurycoma longifolia appears to be safe for long-term use when taken as directed. Unlike synthetic testosterone replacement, it works by optimizing the body's natural hormone production pathways, which may reduce the risk of negative feedback loops or dependency issues. However, as with any supplement, it's always best to consult with a healthcare professional before starting long-term use.

Q5. How does Eurycoma longifolia compare to synthetic testosterone replacement therapy? Eurycoma longifolia offers a natural alternative to synthetic testosterone replacement therapy. It stimulates the body's own testosterone production rather than introducing external hormones. This approach may result in fewer side effects and doesn't interfere with the body's natural regulatory mechanisms. Additionally, standardized extracts like LJ100® ensure consistent potency while adhering to anti-doping regulations, making it a viable option for athletes.

Got questions? Ask the author in the comments section at the bottom of this page.

Dr. Peter Kassner, NMD - Biography

Dr. Peter Kassner, NMD, is the founding CEO of Health Natura, bringing 29 years of painstaking dedication to the field of naturopathic medicine. His journey in natural healing began in 1993 at the age of 17, when he embarked on his first apprenticeship before even completing high school...

Dr. Kassner established his first pain clinic, Clinical Therapeutics, in Tuscaloosa, Alabama, in 1996. This eventually evolved into Health Natura, LLC in 2005, reflecting his expanded mission to make Integrative Medicine accessible to those seeking alternatives to conventional treatments.

Throughout his clinical career, Dr. Kassner developed Unparalleled Expertise in immunology, cancer treatment protocols, endocrinology, acute and chronic infectious disease management, neuro-immunology, endocrine-immunology, thyroid iodine therapy, and Lyme disease interventions. His extensive training includes certifications in clinical massage, cranial sacral therapy, energy medicine, homeopathy, herbology, Chinese herbology, acupuncture, reflexology, EAV energy diagnostics, IV chelation, chemistry, and supplement compounding.

After obtaining both Masters and Doctoral degrees in Naturopathic Medicine, in 2005, dissatisfied with the state of commercial supplements, Dr. Kassner established Health Natura's first laboratory, specializing in Custom Compounding of preservative-free, excipient-free formulations with minimal ingredients. This commitment to purity and efficacy led him to retire from clinical practice in 2012 to focus entirely on Health Natura's supplement program.

Dr. Kassner's approach to naturopathic medicine has been profoundly shaped by his extensive travels throughout Western countries and Asia, where he studied diverse healing traditions. This global perspective informs his unique philosophy: delivering High-Quality, Personalized Wellness Solutions rather than mass-produced alternatives with compromised ingredients...

Today, Dr. Kassner continues to revolutionize the supplement industry through careful formulation and ethical sourcing, making Health Natura a trusted resource for those seeking superior natural health products.

* These statements have not been evaluated by the FDA (Food and Drug Administration). This product is not intended to treat, cure or prevent any disease. Statements of potential therapeutic value are the opinion of Dr. Kassner, ND, and are based on his personal and clinical experience. They should not be construed to endorse, condone or promote the use of any product as a medical treatment for any condition. Consult a medical professional before engaging in any self-care or nutritional supplement regimen to ensure safe and appropriate use. 

Dr. Kassner has been active in the field of alternative medicine since 1991. 

References

[1] - https://pmc.ncbi.nlm.nih.gov/articles/PMC9415500/
[2] - https://pubmed.ncbi.nlm.nih.gov/36013514/
[3] - https://www.mdpi.com/2076-3417/14/11/4372
[4] - https://www.sciencedirect.com/science/article/pii/S1875536417300109
[5] - https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism
[6] - https://www.medicalnewstoday.com/articles/276013
[7] - https://www.auanet.org/guidelines-and-quality/guidelines/testosterone-deficiency-guideline
[8] - https://www.urologyhealth.org/urology-a-z/l/low-testosterone
[9] - https://www.bumc.bu.edu/sexualmedicine/publications/prevalence-diagnosis-and-treatment-of-hypogonadism-in-primary-care-practice/
[10] - https://pmc.ncbi.nlm.nih.gov/articles/PMC6274257/
[11] - https://www.grandviewresearch.com/industry-analysis/testosterone-booster-supplements-market-report
[12] - https://pmc.ncbi.nlm.nih.gov/articles/PMC8254464/
[13] - https://www.sciencedirect.com/science/article/abs/pii/S0378874113004431
[14] - https://onlinelibrary.wiley.com/doi/10.1111/and.14001
[15] - https://www.tandfonline.com/doi/full/10.1186/1550-2783-10-28
[16] - https://pubmed.ncbi.nlm.nih.gov/23810842/
[17] - https://www.nutritionaloutlook.com/view/tongkat-ali-may-support-reproductive-hormones-in-young-males-say-recent-study
[18] - https://foodandnutritionresearch.net/index.php/fnr/article/view/5647
[19] - https://pubmed.ncbi.nlm.nih.gov/23754792/
[20] - https://www.maturitas.org/article/S0378-5122(20)30449-7/abstract
[21] - https://pubmed.ncbi.nlm.nih.gov/26365449/
[22] - https://www.sciencedirect.com/science/article/abs/pii/S1875536417300109
[23] - https://pubmed.ncbi.nlm.nih.gov/23705671/
[24] - https://pmc.ncbi.nlm.nih.gov/articles/PMC3669033/
[25] - https://pmc.ncbi.nlm.nih.gov/articles/PMC3739276/
[26] - https://www.healthline.com/nutrition/tongkat-ali-longjack-review
[27] - https://pmc.ncbi.nlm.nih.gov/articles/PMC4085925/
[28] - https://www.sciencedirect.com/science/article/abs/pii/S1744388120311762